The original paper is in English. Non-English content has been machine-translated and may contain typographical errors or mistranslations. ex. Some numerals are expressed as "XNUMX".
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The original paper is in English. Non-English content has been machine-translated and may contain typographical errors or mistranslations. Copyrights notice
Les technologies élémentaires ont été étudiées pour créer la puce de santé, un système micro-analytique intelligent permettant de détecter les marqueurs de la santé humaine à partir d'une trace de sang. Un processus en deux étapes pour la gravure sèche profonde du quartz a été discuté afin de surmonter les problèmes de défauts de forme concave au fond des rainures. Un revêtement avec un polymère de 2-méthacryloyloxyéthylphosphorylcholine (MPC) a été étudié pour supprimer l'adsorption de biosubstance sur la paroi interne du canal d'écoulement sur la puce et une bonne biocompatibilité a été obtenue pour la suppression de l'adsorption des protéines et de l'adhésion des cellules sanguines. Un prototype de puce médicale a été fabriqué sur une plaque de polyéthylène téréphtalate (PET) à l'aide d'une technique de micromoulage. Grâce à cette puce, les concentrations d'ions pH, Na+K+Ca++ ont été mesurés avec succès avec des transistors à effet de champ sensibles aux ions (ISFET) intégrés.
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Akio OKI, Yuzuru TAKAMURA, Takayuki FUKASAWA, Hiroki OGAWA, Yoshitaka ITO, Takanori ICHIKI, Yasuhiro HORIIKE, "Study on Elemental Technologies for Creation of Healthcare Chip Fabricated on Polyethylene Terephthalate Plate" in IEICE TRANSACTIONS on Electronics,
vol. E84-C, no. 12, pp. 1801-1806, December 2001, doi: .
Abstract: Elemental technologies have been studied to establish the healthcare chip which is an intelligent micro analytical system to detect human health markers from a trail of blood. A two steps process for deep quartz dry-etching was discussed in order to overcome the issues of concave-shaped defects at the bottom of grooves. A coating with 2-methacryloyloxyethylphosphorylcholine (MPC) polymer was studied to suppress the adsorption of bio-substance onto the inner wall of the flow channel on chip and good bio-compatibility was achieved for suppression of protein adsorption and blood cell adhesion. A prototype of healthcare chip was fabricated on polyethylene terephthalate (PET) plate using a micro molding technique. Using this chip, the ion concentrations of pH, Na+, K+, Ca++ were successfully measured with embedded ion sensitive field effect transistors (ISFET's).
URL: https://global.ieice.org/en_transactions/electronics/10.1587/e84-c_12_1801/_p
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@ARTICLE{e84-c_12_1801,
author={Akio OKI, Yuzuru TAKAMURA, Takayuki FUKASAWA, Hiroki OGAWA, Yoshitaka ITO, Takanori ICHIKI, Yasuhiro HORIIKE, },
journal={IEICE TRANSACTIONS on Electronics},
title={Study on Elemental Technologies for Creation of Healthcare Chip Fabricated on Polyethylene Terephthalate Plate},
year={2001},
volume={E84-C},
number={12},
pages={1801-1806},
abstract={Elemental technologies have been studied to establish the healthcare chip which is an intelligent micro analytical system to detect human health markers from a trail of blood. A two steps process for deep quartz dry-etching was discussed in order to overcome the issues of concave-shaped defects at the bottom of grooves. A coating with 2-methacryloyloxyethylphosphorylcholine (MPC) polymer was studied to suppress the adsorption of bio-substance onto the inner wall of the flow channel on chip and good bio-compatibility was achieved for suppression of protein adsorption and blood cell adhesion. A prototype of healthcare chip was fabricated on polyethylene terephthalate (PET) plate using a micro molding technique. Using this chip, the ion concentrations of pH, Na+, K+, Ca++ were successfully measured with embedded ion sensitive field effect transistors (ISFET's).},
keywords={},
doi={},
ISSN={},
month={December},}
Copier
TY - JOUR
TI - Study on Elemental Technologies for Creation of Healthcare Chip Fabricated on Polyethylene Terephthalate Plate
T2 - IEICE TRANSACTIONS on Electronics
SP - 1801
EP - 1806
AU - Akio OKI
AU - Yuzuru TAKAMURA
AU - Takayuki FUKASAWA
AU - Hiroki OGAWA
AU - Yoshitaka ITO
AU - Takanori ICHIKI
AU - Yasuhiro HORIIKE
PY - 2001
DO -
JO - IEICE TRANSACTIONS on Electronics
SN -
VL - E84-C
IS - 12
JA - IEICE TRANSACTIONS on Electronics
Y1 - December 2001
AB - Elemental technologies have been studied to establish the healthcare chip which is an intelligent micro analytical system to detect human health markers from a trail of blood. A two steps process for deep quartz dry-etching was discussed in order to overcome the issues of concave-shaped defects at the bottom of grooves. A coating with 2-methacryloyloxyethylphosphorylcholine (MPC) polymer was studied to suppress the adsorption of bio-substance onto the inner wall of the flow channel on chip and good bio-compatibility was achieved for suppression of protein adsorption and blood cell adhesion. A prototype of healthcare chip was fabricated on polyethylene terephthalate (PET) plate using a micro molding technique. Using this chip, the ion concentrations of pH, Na+, K+, Ca++ were successfully measured with embedded ion sensitive field effect transistors (ISFET's).
ER -